快三彩票app送彩金

快三彩票app送彩金

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  • Molecular design tools and large virtual libraries of constrained scaffolds, collectively known as Vectrix™—allows for the de novo selection of peptide scaffolds as starting points against specific targets based on computational matching to functional structures of the intended targets
  • Random/structure-based libraries and phage display techniques—allows for the discovery and optimization of peptide hits in a de novo and/or focused manner
  • Oral stability assaysin vitroandex vivo assays and systems that simulate chemical and biological degradative mechanisms, and physical barriers that constrained peptides must overcome for oral stability and absorption
  • Formulation—integration of known and novel technologies to deliver stable peptides through oral, subcutaneous, and rectal dosage forms to optimize treatment options for patients
  • Medicinal peptide chemistry—allows optimization and refinement of potency, selectivity, oral and plasma stability and GI restriction
  • In vivoandex vivo pharmacology studies for GI restriction—tools to quantify compound concentrations and activity in various GI tissue compartments to develop oral products with GI stability and minimal systemic exposure

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  • PTG-300—injectable hepcidin peptide mimetic for rare blood disorders
  • PN-943andPTG-200—oral antagonist peptide candidates for IBD

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